As discussed in a previous article in this series (An Introduction To Biopharmaceutical Facility Design & Layout), there are multiple variables that must be considered in the layout of a biopharmaceutical facility, and many of these variables are interdependent. This article will explore a critical but often overlooked component of bioprocess facility design — HVAC systems — and the realities of HVAC compliance and methods. HVAC is the single continuous and active system that removes the bioburden and particulates introduced by the facilities’ single most contaminating source, humans!
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